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Assay Detail

CHEMBL780734

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was tested for its D-1 activity in rat caudate nuclei
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Confidence 1 — Organism
Curated By Intermediate

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

Synthesis and renal vasodilator activity of some dopamine agonist 1-aryl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diols: halogen and methyl analogues of fenoldopam.
Weinstock J, Ladd DL, Wilson JW, Brush CK, Yim NC, Gallagher G, McCarthy ME, Silvestri J, Sarau HM, Flaim KE.
J Med Chem (1986) 29 : 2315 -2325
PubMed 2878077 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 7.10 7.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL286080 SKF-38393 1 7.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL286080 SKF-38393 EC50 = 80.0 nM 7.10