Assay Detail
Functional
CHEMBL780736
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for its vasodilator effects on endothelium-denuded strips of rat aorta precontracted with noradrenaline in the presence of oxyhemoglobin
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Aorta |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Furoxans as nitric oxide donors. 4-Phenyl-3-furoxancarbonitrile: thiol-mediated nitric oxide release and biological evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 8.02 | 8.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL336467 | FUROXAN | — | 1 | 8.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL336467 | FUROXAN | EC50 | = | 9.5 | nM | 8.02 |