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Assay Detail

CHEMBL782322

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was tested for inhibition of glucose transport in adipocytes plasma membrane vesicles using [H]-forskolin as radioligand
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Confidence 1 — Organism
Curated By Intermediate

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

On the analogy between forskolin and D-glucose.
Abbadi M, Morin C.
Bioorg Med Chem Lett (1999) 9 : 1779 -1782
PubMed 10406641 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 2 5.89 6.62

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL52606 COLFORSIN 2.0 1 6.62
CHEMBL486619 1 5.15

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL52606 COLFORSIN EC50 = 240.0 nM 6.62
CHEMBL486619 EC50 = 7100.0 nM 5.15