Assay Detail
Functional
CHEMBL782882
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Compound tested to inhibit (LPO) lipid peroxidation was determined in rat brain microsomes
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Subcellular | Microsomes |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Phenolic thiazoles as novel orally-active neuroprotective agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.33 | 6.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL291287 | — | — | 1 | 6.27 |
| CHEMBL288720 | — | — | 1 | 6.03 |
| CHEMBL146 | BUTYLATED HYDROXYTOLUENE | 2.0 | 1 | 4.52 |
| CHEMBL290916 | EDARAVONE | 4.0 | 1 | 4.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL291287 | — | IC50 | = | 540.0 | nM | 6.27 |
| CHEMBL288720 | — | IC50 | = | 930.0 | nM | 6.03 |
| CHEMBL146 | BUTYLATED HYDROXYTOLUENE | IC50 | = | 30000.0 | nM | 4.52 |
| CHEMBL290916 | EDARAVONE | IC50 | = | 32000.0 | nM | 4.50 |