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Assay Detail

CHEMBL783635

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antagonist activity against amylase secretion from rat pancreatic acini
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Confidence 1 — Organism
Curated By Intermediate

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

On the significance of the C-terminal primary amide in cholecystokinin
Rolland M, Lignon M, Galas M, Bernad N, Rodriguez M, Fulcrand P, Martinez J
Bioorg Med Chem Lett (1993) 3 : 851 -854
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.55 4.58

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL413186 1 4.58
CHEMBL216527 1 4.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL413186 IC50 = 26000.0 nM 4.58
CHEMBL216527 IC50 = 30000.0 nM 4.52