Assay Detail
Functional
CHEMBL784019
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Compound was evaluated in vivo for inhibition of Ovalbumin induced rhinitis in anesthetized rats after topical administration (nasal perfusion).
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
New N-(pyridin-4-yl)-(indol-3-yl)acetamides and propanamides as antiallergic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.88 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL160259 | — | — | 1 | 6.60 |
| CHEMBL1305 | ANTAZOLINE | 4.0 | 1 | 5.90 |
| CHEMBL511 | PYRILAMINE | 4.0 | 1 | 5.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL160259 | — | IC50 | = | 250.0 | nM | 6.60 |
| CHEMBL1305 | ANTAZOLINE | IC50 | = | 1260.0 | nM | 5.90 |
| CHEMBL511 | PYRILAMINE | IC50 | = | 7410.0 | nM | 5.13 |