Assay Detail
Functional
CHEMBL784214
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Percent inhibition of glutamate activity against cGMP was determined
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
(R)-4-oxo-5-phosphononorvaline: a new competitive glutamate antagonist at the NMDA receptor complex.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.48 | 6.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL22304 | — | — | 1 | 6.10 |
| CHEMBL39664 | SELFOTEL | 2.0 | 1 | 5.96 |
| CHEMBL28862 | — | — | 1 | 5.26 |
| CHEMBL431029 | — | — | 1 | 5.23 |
| CHEMBL274440 | AP-7 | — | 1 | 4.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL22304 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL39664 | SELFOTEL | IC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL28862 | — | IC50 | = | 5500.0 | nM | 5.26 |
| CHEMBL431029 | — | IC50 | = | 5900.0 | nM | 5.23 |
| CHEMBL274440 | AP-7 | IC50 | = | 14100.0 | nM | 4.85 |