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Assay Detail

CHEMBL784390

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiallergic activity in in vitro antigen-induced histamine release from isolated mast cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Confidence 1 — Organism
Curated By Expert

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

Substituted 6,7-dihydroimidazo[1,2-a]purin-9(4H)-ones.
Temple DL, Yevich JP, Catt JD, Owens D, Hanning C, Covington RR, Seidehamel RJ, Dungan KW.
J Med Chem (1980) 23 : 1188 -1198
PubMed 6161252 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.10 5.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL74 CROMOLYN SODIUM 4.0 1 5.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL74 CROMOLYN SODIUM IC50 = 8000.0 nM 5.10