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Assay Detail

CHEMBL786453

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Binding
Binding affinity for glucocorticoid receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Expert

Target

Glucocorticoid receptor (CHEMBL2034)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthesis and characterization of non-steroidal ligands for the glucocorticoid receptor: selective quinoline derivatives with prednisolone-equivalent functional activity.
Coghlan MJ, Kym PR, Elmore SW, Wang AX, Luly JR, Wilcox D, Stashko M, Lin CW, Miner J, Tyree C, Nakane M, Jacobson P, Lane BC.
J Med Chem (2001) 44 : 2879 -2885
PubMed 11520196 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.15 8.15

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL419158 1 8.15

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL419158 Ki = 7.1 nM 8.15