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Assay Detail

CHEMBL789200

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound was tested for its ability to inhibit kainic acid (KA)-induced inward currents in Xenopus oocytes injected with poly {A+) mRNA from rats
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Confidence 1 — Organism
Curated By Intermediate

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

Synthesis and glutamate antagonist activity of 4-phosphonoalkylquinoline derivatives: A novel class of non-NMDA antagonist
Hamilton G, Bednar D, Borosky S, Huang Z, Zubrowski R, Ferkany J, Karbon E
Bioorg Med Chem Lett (1994) 4 : 2035 -2040
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.46 5.46

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL284012 1 5.46

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL284012 Ki = 3500.0 nM 5.46