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Assay Detail

CHEMBL789209

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Concentration inhibiting 5-HT reuptake in rat brain synaptosomes.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Tissue Brain
Confidence 1 — Organism
Curated By Intermediate

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

A new single-photon emission computed tomography imaging agent for serotonin transporters: [123I]IDAM, 5-iodo-2-((2-((dimethylamino)methyl)phenyl)thio)benzyl alcohol.
Oya S, Kung MP, Acton PD, Mu M, Hou C, Kung HF.
J Med Chem (1999) 42 : 333 -335
PubMed 9986702 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.40 9.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL361259 1 9.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL361259 Ki = 0.4 nM 9.40