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Assay Detail

CHEMBL790103

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
In vitro concentration required to displace [125I]L-T3 from rat hepatic nuclei.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Confidence 1 — Organism
Curated By Intermediate

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

alpha-Methylated analogues of triiodothyroalkanoic acids: synthesis and biological activity.
Zenker N, Ekpe AE, Hubbard LS.
J Med Chem (1992) 35 : 548 -552
PubMed 1738147 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.10 9.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL41632 TIRATRICOL 3.0 1 9.10

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL41632 TIRATRICOL Ki = 0.79 nM 9.10