Assay Detail
Functional
CHEMBL793162
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Value was obtained against serotonin-induced (5-HT2A) contractions in rat aorta rings
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Aorta |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and atypical antipsychotic profile of some 2-(2-piperidinoethyl)benzocycloalkanones as analogues of butyrophenone.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 4 | 7.61 | 8.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL87717 | — | — | 1 | 8.12 |
| CHEMBL87458 | — | — | 1 | 8.12 |
| CHEMBL87943 | — | — | 1 | 7.45 |
| CHEMBL87026 | — | — | 1 | 6.75 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL87717 | — | Kd | = | 7.586 | nM | 8.12 |
| CHEMBL87458 | — | Kd | = | 7.586 | nM | 8.12 |
| CHEMBL87943 | — | Kd | = | 35.48 | nM | 7.45 |
| CHEMBL87026 | — | Kd | = | 177.83 | nM | 6.75 |