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Assay Detail

CHEMBL795233

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of microsomal lipid peroxidation induced by CCl4/NADPH in rat liver
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Tissue Liver
Confidence 1 — Organism
Curated By Intermediate

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

Synthesis and pharmacological evaluation of 2'-hydroxychalcones and flavones as inhibitors of inflammatory mediators generation.
Ballesteros JF, Sanz MJ, Ubeda A, Miranda MA, Iborra S, Payá M, Alcaraz MJ.
J Med Chem (1995) 38 : 2794 -2797
PubMed 7629818 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.35 5.35

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL7983 PROPYL GALLATE 1.0 1 5.35

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL7983 PROPYL GALLATE IC50 = 4500.0 nM 5.35