Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL796030

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Tested for intravenous anti-oxytocic effect in in vivo in rats
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Confidence 1 — Organism
Curated By Intermediate

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

[1-beta-Mercapto-beta,beta-cyclopentamethylenepropionic acid),2-(O-methyl)tyrosine ]argine-vasopressin and [1-beta-mercapto-beta,beta-cyclopentamethylenepropionic acid)]argine-vasopressine, two highly potent antagonists of the vasopressor response to arginine-vasopressin.
Kruszynski M, Lammek B, Manning M, Seto J, Haldar J, Sawyer WH.
J Med Chem (1980) 23 : 364 -368
PubMed 6892930 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 6.71 6.79

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL266176 1 6.79
CHEMBL2370569 1 6.62

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL266176 Kd = 162.18 nM 6.79
CHEMBL2370569 Kd = 239.88 nM 6.62