Assay Detail
Functional
CHEMBL797552
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activity tested at cloned rat mGluR2 receptor expressed in Chinese Hamster Ovary (CHO) cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Cell Type | CHO |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Metabotropic glutamate receptor 2 (CHEMBL2851) ↗| Type | SINGLE PROTEIN |
| Organism | Rattus norvegicus |
Publication
Synthesis and anticonvulsant activity of novel bicyclic acidic amino acids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 5.25 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL34453 | — | — | 1 | 5.70 |
| CHEMBL322887 | — | — | 1 | 4.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL34453 | — | EC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL322887 | — | EC50 | = | 16000.0 | nM | 4.80 |