Assay Detail
Functional
CHEMBL797572
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Effective concentration required for stimulation of [35S]GTP-gamma-S, binding in rat microsomal membranes
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel analogues of arachidonylethanolamide (anandamide): affinities for the CB1 and CB2 cannabinoid receptors and metabolic stability.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 5 | 6.72 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL359165 | — | — | 1 | 7.00 |
| CHEMBL559612 | CP-55940 | — | 1 | 7.00 |
| CHEMBL188 | WIN-552122 | — | 1 | 6.75 |
| CHEMBL120526 | METHANANDAMIDE | — | 1 | 6.48 |
| CHEMBL151167 | — | — | 1 | 6.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL359165 | — | EC50 | = | 100.0 | nM | 7.00 |
| CHEMBL559612 | CP-55940 | EC50 | = | 100.0 | nM | 7.00 |
| CHEMBL188 | WIN-552122 | EC50 | = | 180.0 | nM | 6.75 |
| CHEMBL120526 | METHANANDAMIDE | EC50 | = | 330.0 | nM | 6.48 |
| CHEMBL151167 | — | EC50 | = | 420.0 | nM | 6.38 |