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Assay Detail

CHEMBL797693

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibitory concentration for [3H]PCP binding to rat brain homogenate relative to PCP
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Tissue Brain
Confidence 1 — Organism
Curated By Intermediate

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

Structure-activity relationships of the cycloalkyl ring of phencyclidine.
McQuinn RL, Cone EJ, Shannon HE, Su TP.
J Med Chem (1981) 24 : 1429 -1432
PubMed 7310819 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.57 6.57

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL542581 PHENCYCLIDINE HYDROCHLORIDE -1.0 1 6.57

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL542581 PHENCYCLIDINE HYDROCHLORIDE IC50 = 270.0 nM 6.57