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Assay Detail

CHEMBL797778

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Neuroprotective action was estimated in terms of its inhibitory concentration against superoxide and hydroxyl radicals measured by the leakage of cytoplasmic enzyme lactate dehydrogenase (LDH).
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Confidence 1 — Organism
Curated By Intermediate

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

Synthesis and evaluation of 4-hydroxyphenylacetic acid amides and 4-hydroxycinnamamides as antioxidants.
Jung YS, Kang TS, Yoon JH, Joe BY, Lim HJ, Seong CM, Park WK, Kong JY, Cho J, Park NS.
Bioorg Med Chem Lett (2002) 12 : 2599 -2602
PubMed 12182869 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.00 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL87037 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL87037 IC50 = 100.0 nM 7.00