Assay Detail
Functional
CHEMBL797933
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Compound was tested for inhibition of [3H]dopamine against rat striatum using in vitro biogenic amine uptake assay using rat brain synaptosomes.
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Striatum |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Substituted (pyrroloamino)pyridines: potential agents for the treatment of Alzheimer's disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.39 | 6.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL29835 | BESIPIRDINE | 2.0 | 1 | 6.39 |
| CHEMBL350442 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL29835 | BESIPIRDINE | IC50 | = | 410.0 | nM | 6.39 |
| CHEMBL350442 | — | IC50 | > | 20000.0 | nM | - |