Assay Detail
Binding
CHEMBL798316
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [3H]9-cis-RA binding to RXR alpha receptor
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthesis and structure-activity relationships of potent conformationally restricted retinoid X receptor ligands
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 7.73 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL93518 | — | — | 1 | 8.52 |
| CHEMBL92284 | — | — | 1 | 8.40 |
| CHEMBL1023 | BEXAROTENE | 4.0 | 1 | 7.85 |
| CHEMBL93848 | — | — | 1 | 7.04 |
| CHEMBL96184 | — | — | 1 | 6.82 |
| CHEMBL92394 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL93518 | — | Ki | = | 3.0 | nM | 8.52 |
| CHEMBL92284 | — | Ki | = | 4.0 | nM | 8.40 |
| CHEMBL1023 | BEXAROTENE | Ki | = | 14.0 | nM | 7.85 |
| CHEMBL93848 | — | Ki | = | 92.0 | nM | 7.04 |
| CHEMBL96184 | — | Ki | = | 150.0 | nM | 6.82 |
| CHEMBL92394 | — | Ki | > | 1000.0 | nM | - |