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Assay Detail

CHEMBL798362

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Functional
Tested for the dissociation constant for [125I]MPPI to rat hippocampal homogenates
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Tissue Hippocampus
Confidence 1 — Organism
Curated By Intermediate

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

Derivatives of 4-(2'-methoxyphenyl)-1-[2'-(N-2"-pyridinyl-p-iodobenzamido)ethyl]pipera zine (p-MPPI) as 5-HT1A ligands.
Zhuang ZP, Kung MP, Chumpradit S, Mu M, Kung HF.
J Med Chem (1994) 37 : 4572 -4575
PubMed 7799409 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 9.52 9.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL286607 1 9.52
CHEMBL29027 1 9.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL286607 Kd = 0.3 nM 9.52
CHEMBL29027 Kd = 0.3 nM 9.52