Assay Detail
Functional
CHEMBL798406
Review assay metadata, readout intent, target linkage, and publication context from the same page.
pA2 data of Compound was evaluated for tissue contractions in isolated rat prostatic tissue strips.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Novel arylpiperazines as selective alpha1-adrenergic receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 7.33 | 7.79 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL12529 | — | — | 1 | 7.79 |
| CHEMBL275469 | RWJ-38063 | — | 1 | 7.50 |
| CHEMBL12603 | RWJ-68157 | — | 1 | 6.69 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL12529 | — | Kd | = | 16.22 | nM | 7.79 |
| CHEMBL275469 | RWJ-38063 | Kd | = | 31.62 | nM | 7.50 |
| CHEMBL12603 | RWJ-68157 | Kd | = | 204.17 | nM | 6.69 |