Assay Detail
Functional
CHEMBL798409
Review assay metadata, readout intent, target linkage, and publication context from the same page.
pA2 value by AVP (V1a) stimulated contraction of the isolated rat tail artery
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Tail |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Development of a novel class of cyclic hexapeptide oxytocin antagonists based on a natural product.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.31 | 6.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2112249 | — | — | 1 | 6.55 |
| CHEMBL1790937 | — | — | 1 | 6.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2112249 | — | Kd | = | 281.84 | nM | 6.55 |
| CHEMBL1790937 | — | Kd | = | 870.96 | nM | 6.06 |