Assay Detail
Binding
CHEMBL798962
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Binding affinity against S-adenosyl-homocysteine hydrolase
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Potential inhibitors of S-adenosylmethionine-dependent methyltransferases. 9. 2',3'-Dialdehyde derivatives of carbocyclic purine nucleosides as inhibitors of S-adenosylhomocysteine hydrolase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.67 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL268272 | 3-DEAZAARISTEROMYCIN A | — | 1 | 8.40 |
| CHEMBL49935 | ARISTEROMYCIN | — | 1 | 6.96 |
| CHEMBL26801 | — | — | 1 | 4.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL268272 | 3-DEAZAARISTEROMYCIN A | Ki | = | 4.0 | nM | 8.40 |
| CHEMBL49935 | ARISTEROMYCIN | Ki | = | 110.0 | nM | 6.96 |
| CHEMBL26801 | — | Ki | = | 22000.0 | nM | 4.66 |