Assay Detail
Binding
CHEMBL799065
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of microcystin analogues to catalytic subunits of Serine/threonine protein phosphatase 2A (PP2Ac)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Serine-threonine protein phosphatase 2A regulatory subunit (CHEMBL2669) ↗| Type | SINGLE PROTEIN |
| Organism | Gallus gallus |
Publication
Serine-threonine protein phosphatase inhibitors: development of potential therapeutic strategies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 8.74 | 9.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL17738 | MICROCYSTIN-LA | — | 1 | 9.52 |
| CHEMBL15785 | — | — | 1 | 8.82 |
| CHEMBL385212 | — | — | 1 | 8.82 |
| CHEMBL17060 | — | — | 1 | 8.47 |
| CHEMBL1159778 | — | — | 1 | 8.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL17738 | MICROCYSTIN-LA | IC50 | = | 0.3 | nM | 9.52 |
| CHEMBL15785 | — | IC50 | = | 1.5 | nM | 8.82 |
| CHEMBL385212 | — | IC50 | = | 1.5 | nM | 8.82 |
| CHEMBL17060 | — | IC50 | = | 3.4 | nM | 8.47 |
| CHEMBL1159778 | — | IC50 | = | 9.0 | nM | 8.05 |