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Assay Detail

CHEMBL799114

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Potency was evaluated on rabbit heart serotonergic receptors
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Oryctolagus cuniculus
Confidence 4 — Cell-line / Tissue
Curated By Autocuration

Target

Serotonin (5-HT) receptor (CHEMBL2096904)
Type PROTEIN FAMILY
Organism Homo sapiens

Publication

5-HT3 antagonists derived from aminopyridazine-type muscarinic M1 agonists.
Rival Y, Hoffmann R, Didier B, Rybaltchenko V, Bourguignon JJ, Wermuth CG.
J Med Chem (1998) 41 : 311 -317
PubMed 9464362 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 9.80 9.80

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL323208 1 9.80

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL323208 Kd = 0.1585 nM 9.80