Assay Detail
Binding
CHEMBL799698
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Effective concentration against retinoid receptor isoform (RAR gamma) expressed in CV-1 cells
20
Total Activities
20
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | CV-1 |
| Confidence | 8 — Homologous single protein target |
| Curated By | Expert |
Publication
Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 20 | 6.10 | 6.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL96184 | — | — | 1 | 6.58 |
| CHEMBL330593 | — | — | 1 | 6.40 |
| CHEMBL419166 | — | — | 1 | 5.99 |
| CHEMBL101609 | — | — | 1 | 5.84 |
| CHEMBL101308 | — | — | 1 | 5.69 |
| CHEMBL101302 | — | — | 1 | - |
| CHEMBL1023 | BEXAROTENE | 4.0 | 1 | - |
| CHEMBL102039 | — | — | 1 | - |
| CHEMBL101666 | — | — | 1 | - |
| CHEMBL97910 | — | — | 1 | - |
| CHEMBL98142 | — | — | 1 | - |
| CHEMBL99325 | — | — | 1 | - |
| CHEMBL318916 | — | — | 1 | - |
| CHEMBL328419 | — | — | 1 | - |
| CHEMBL100986 | — | — | 1 | - |
| CHEMBL100623 | — | — | 1 | - |
| CHEMBL101212 | — | — | 1 | - |
| CHEMBL98172 | — | — | 1 | - |
| CHEMBL101661 | — | — | 1 | - |
| CHEMBL101712 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL96184 | — | EC50 | = | 266.0 | nM | 6.58 |
| CHEMBL330593 | — | EC50 | = | 397.0 | nM | 6.40 |
| CHEMBL419166 | — | EC50 | = | 1016.0 | nM | 5.99 |
| CHEMBL101609 | — | EC50 | = | 1446.0 | nM | 5.84 |
| CHEMBL101308 | — | EC50 | = | 2043.0 | nM | 5.69 |
| CHEMBL101302 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL1023 | BEXAROTENE | EC50 | > | 10000.0 | nM | - |
| CHEMBL102039 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL101666 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL97910 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL98142 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL99325 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL318916 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL328419 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL100986 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL100623 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL101212 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL98172 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL101661 | — | EC50 | > | 10000.0 | nM | - |
| CHEMBL101712 | — | EC50 | > | 10000.0 | nM | - |