Assay Detail
Functional
CHEMBL799762
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Binding affinity was determined
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
2-O-alkyltyrosine derivatives of 1-deamino-arginine-vasopressin: highly specific and potent antidiuretic agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 6 | 7.07 | 7.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL386280 | — | — | 1 | 7.54 |
| CHEMBL274636 | — | — | 1 | 7.07 |
| CHEMBL435323 | — | — | 1 | 7.03 |
| CHEMBL262753 | — | — | 1 | 7.01 |
| CHEMBL268780 | — | — | 1 | 6.90 |
| CHEMBL217307 | — | — | 1 | 6.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL386280 | — | Kd | = | 28.84 | nM | 7.54 |
| CHEMBL274636 | — | Kd | = | 85.11 | nM | 7.07 |
| CHEMBL435323 | — | Kd | = | 93.33 | nM | 7.03 |
| CHEMBL262753 | — | Kd | = | 97.72 | nM | 7.01 |
| CHEMBL268780 | — | Kd | = | 125.89 | nM | 6.90 |
| CHEMBL217307 | — | Kd | = | 128.82 | nM | 6.89 |