Assay Detail
Functional
CHEMBL799764
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive antagonism against serotonin-induced contractions in rat aorta ring stripped of endothelium
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Aorta |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Butyrophenone analogues: Synthesis of 2-methyl-3-ethyl-5-aminoethyl-4,5,6,7-tetrahydroindol-4-ones, and their affinities for d1, d2 and 5-ht2a receptors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 6.58 | 6.98 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL349997 | — | — | 1 | 6.98 |
| CHEMBL460 | MOLINDONE | 4.0 | 1 | 6.18 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL349997 | — | Kd | = | 104.71 | nM | 6.98 |
| CHEMBL460 | MOLINDONE | Kd | = | 660.69 | nM | 6.18 |