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Assay Detail

CHEMBL799767

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound at an oral dose of 10 mg/Kg was tested ex vivo in rat after 5 hr against platelet aggregation induced by U-46,619
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Rattus norvegicus
Confidence 1 — Organism
Curated By Intermediate

Target

Rattus norvegicus (CHEMBL376)
Type ORGANISM
Organism Rattus norvegicus

Publication

A novel approach to dual-acting thromboxane receptor antagonist/synthase inhibitors based on the link of 1,3-dioxane-thromboxane receptor antagonists and -thromboxane synthase inhibitors.
Ackerley N, Brewster AG, Brown GR, Clarke DS, Foubister AJ, Griffin SJ, Hudson JA, Smithers MJ, Whittamore PR.
J Med Chem (1995) 38 : 1608 -1628
PubMed 7752186 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 7.00 7.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL30024 1 7.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL30024 Kd = 100.0 nM 7.00