Assay Detail
Functional
CHEMBL800358
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Concentration that produces 50% of the maximal response to compound in rat thoracic aorta strips in the presence of PBZ and IDA at 1 uM
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Thoracic aorta |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and biological activities of a new set of irreversibly acting 2-(4'-isothiocyanatobenzyl)imidazoline analogs in rat thoracic aorta.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 4.27 | 4.27 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL59034 | — | — | 1 | 4.27 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL59034 | — | EC50 | = | 54000.0 | nM | 4.27 |