Assay Detail
Functional
CHEMBL800380
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Compound was evaluated for its inhibitory concentration against [Fe2+]/AA- induced oxidative neuronal damage in primary cultured rat cortical cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and evaluation of 4-hydroxyphenylacetic acid amides and 4-hydroxycinnamamides as antioxidants.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.94 | 5.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL87037 | — | — | 1 | 5.62 |
| CHEMBL312901 | — | — | 1 | 4.62 |
| CHEMBL86670 | — | — | 1 | 4.57 |
| CHEMBL153 | TROLOX | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL87037 | — | IC50 | = | 2400.0 | nM | 5.62 |
| CHEMBL312901 | — | IC50 | = | 23700.0 | nM | 4.62 |
| CHEMBL86670 | — | IC50 | = | 26800.0 | nM | 4.57 |
| CHEMBL153 | TROLOX | IC50 | = | 430530.0 | nM | - |