Assay Detail
Functional
CHEMBL800383
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Neuroprotective action was estimated in terms of its inhibitory concentration against [Fe2+]/AA- induced toxicity
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and evaluation of 4-hydroxyphenylacetic acid amides and 4-hydroxycinnamamides as antioxidants.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.04 | 5.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL280070 | — | — | 1 | 5.38 |
| CHEMBL87809 | — | — | 1 | 5.27 |
| CHEMBL87041 | — | — | 1 | 4.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL280070 | — | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL87809 | — | IC50 | = | 5400.0 | nM | 5.27 |
| CHEMBL87041 | — | IC50 | = | 34200.0 | nM | 4.47 |