Assay Detail
Functional
CHEMBL800395
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Compound was tested for inhibition of [3H]5-HT against rat whole brain using in vitro biogenic amine uptake assay using rat brain synaptosomes.
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Substituted (pyrroloamino)pyridines: potential agents for the treatment of Alzheimer's disease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.58 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL29835 | BESIPIRDINE | 2.0 | 1 | 5.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL29835 | BESIPIRDINE | IC50 | = | 2600.0 | nM | 5.58 |