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Assay Detail

CHEMBL800845

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of the probe bound to Ribonuclease L by compound in radiobinding assay was evaluated
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

2-5A-dependent ribonuclease (CHEMBL3575)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Convergent synthesis of ribonuclease L-active 2',5'-oligoadenylate-peptide nucleic acids.
Wang Z, Chen L, Bayly SF, Torrence PF.
Bioorg Med Chem Lett (2000) 10 : 1357 -1360
PubMed 10890163 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.89 7.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL414948 1 7.89

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL414948 IC50 = 13.0 nM 7.89