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Assay Detail

CHEMBL802429

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity against L929 cells AdoHcy hydrolase activity
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type L929
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Adenosylhomocysteinase (CHEMBL2389)
Type SINGLE PROTEIN
Organism Mus musculus

Publication

Antiviral enantiomeric preference for 5'-noraristeromycin.
Siddiqi SM, Chen X, Schneller SW, Ikeda S, Snoeck R, Andrei G, Balzarini J, De Clercq E.
J Med Chem (1994) 37 : 551 -554
PubMed 8120872 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 8.24 8.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL8771 NEOPLANOCIN A 1 8.52
CHEMBL8275 1 7.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL8771 NEOPLANOCIN A Ki = 3.0 nM 8.52
CHEMBL8275 Ki = 11.1 nM 7.96