Assay Detail
Functional
CHEMBL802947
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The compound was tested for the cytotoxicity against S180 cell lines
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | CCRF S-180 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
9-substituted acridine derivatives with long half-life and potent antitumor activity: synthesis and structure-activity relationships.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.68 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL321473 | — | — | 1 | 7.52 |
| CHEMBL444329 | — | — | 1 | 7.16 |
| CHEMBL109928 | — | — | 1 | 7.01 |
| CHEMBL326274 | — | — | 1 | 5.97 |
| CHEMBL109468 | — | — | 1 | 5.74 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL321473 | — | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL444329 | — | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL109928 | — | IC50 | = | 97.0 | nM | 7.01 |
| CHEMBL326274 | — | IC50 | = | 1070.0 | nM | 5.97 |
| CHEMBL109468 | — | IC50 | = | 1830.0 | nM | 5.74 |