Assay Detail
Functional
CHEMBL803557
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Electropharmacology on rat cortical slice preparation for EAA-evoked depolarizations; Depolarization evoked by the compound is antagonised by 10 uM of CPP.
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and enantiopharmacology of new AMPA-kainate receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 4.96 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL291278 | N-METHYL-D-ASPARTIC ACID (NMDA) | 2.0 | 1 | 4.96 |
| CHEMBL133337 | — | — | 1 | - |
| CHEMBL334583 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL291278 | N-METHYL-D-ASPARTIC ACID (NMDA) | EC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL133337 | — | EC50 | = | 1000000.0 | nM | - |
| CHEMBL334583 | — | EC50 | = | 1000000.0 | nM | - |