Assay Detail
Functional
CHEMBL803570
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Compound was tested for its DPPH radical scavenging activity in rat brain homogenates
11
Total Activities
11
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and evaluation of 4-hydroxyphenylacetic acid amides and 4-hydroxycinnamamides as antioxidants.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 11 | 4.35 | 4.67 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL86670 | — | — | 1 | 4.67 |
| CHEMBL87037 | — | — | 1 | 4.51 |
| CHEMBL312901 | — | — | 1 | 4.46 |
| CHEMBL90392 | — | — | 1 | 4.30 |
| CHEMBL89729 | — | — | 1 | 4.08 |
| CHEMBL87809 | — | — | 1 | 4.05 |
| CHEMBL89879 | — | — | 1 | - |
| CHEMBL280070 | — | — | 1 | - |
| CHEMBL87041 | — | — | 1 | - |
| CHEMBL89474 | — | — | 1 | - |
| CHEMBL327228 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL86670 | — | IC50 | = | 21300.0 | nM | 4.67 |
| CHEMBL87037 | — | IC50 | = | 31000.0 | nM | 4.51 |
| CHEMBL312901 | — | IC50 | = | 34300.0 | nM | 4.46 |
| CHEMBL90392 | — | IC50 | = | 50100.0 | nM | 4.30 |
| CHEMBL89729 | — | IC50 | = | 82200.0 | nM | 4.08 |
| CHEMBL87809 | — | IC50 | = | 89100.0 | nM | 4.05 |
| CHEMBL89879 | — | IC50 | = | 182100.0 | nM | - |
| CHEMBL280070 | — | IC50 | = | 161700.0 | nM | - |
| CHEMBL87041 | — | IC50 | > | 300000.0 | nM | - |
| CHEMBL89474 | — | IC50 | > | 300000.0 | nM | - |
| CHEMBL327228 | — | IC50 | = | 178600.0 | nM | - |