Assay Detail
Binding
CHEMBL803914
Review assay metadata, readout intent, target linkage, and publication context from the same page.
In vitro ability to displace serotonin 5-HT1A receptor binding to rat cerebral cortex in competition experiments against [3H]8-(hydroxy)dipropyl aminotetralin at 15 mg/kg concentration
1
Total Activities
1
Compounds Tested
1
Activity Types
1
Assay Parameters
Assay Information
| Assay Type | Binding |
| Tissue | Cerebral cortex |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
The synthesis and evaluation of the major metabolites of mazapertine
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 8.17 | 8.17 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| DOSE | DOSE | 15.0 | mg.kg-1 | — |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL58053 | — | — | 1 | 8.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL58053 | — | Ki | = | 6.8 | nM | 8.17 |