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Assay Detail

CHEMBL804767

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibitory activity of compound against SSAT extracted from superinduced H157 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type H157
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Diamine acetyltransferase 1 (CHEMBL4286)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Terminally alkylated polyamine analogues as chemotherapeutic agents.
Casero RA, Woster PM.
J Med Chem (2001) 44 : 1 -26
PubMed 11141084 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.20 4.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL86940 1 4.40
CHEMBL33387 1 4.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL86940 IC50 = 40000.0 nM 4.40
CHEMBL33387 IC50 = 100000.0 nM 4.00