Assay Detail
Binding
CHEMBL804829
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Binding affinity was measured for SRIF receptor on AtT-20 mouse pituitary cells
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | Pituitary gland cell |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Expert |
Publication
Modulation of receptor and receptor subtype affinities using diastereomeric and enantiomeric monosaccharide scaffolds as a means to structural and biological diversity. A new route to ether synthesis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 5.00 | 5.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL28824 | — | — | 1 | 5.39 |
| CHEMBL29752 | — | — | 1 | 5.29 |
| CHEMBL28852 | — | — | 1 | 5.25 |
| CHEMBL29102 | — | — | 1 | 5.23 |
| CHEMBL282802 | — | — | 1 | 5.16 |
| CHEMBL29311 | — | — | 1 | 5.10 |
| CHEMBL281200 | — | — | 1 | 5.08 |
| CHEMBL282129 | — | — | 1 | 4.89 |
| CHEMBL281542 | — | — | 1 | 4.85 |
| CHEMBL282618 | — | — | 1 | 4.82 |
| CHEMBL28680 | — | — | 1 | 4.66 |
| CHEMBL282803 | — | — | 1 | 4.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL28824 | — | IC50 | = | 4100.0 | nM | 5.39 |
| CHEMBL29752 | — | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL28852 | — | IC50 | = | 5600.0 | nM | 5.25 |
| CHEMBL29102 | — | IC50 | = | 5900.0 | nM | 5.23 |
| CHEMBL282802 | — | IC50 | = | 7000.0 | nM | 5.16 |
| CHEMBL29311 | — | IC50 | = | 8000.0 | nM | 5.10 |
| CHEMBL281200 | — | IC50 | = | 8400.0 | nM | 5.08 |
| CHEMBL282129 | — | IC50 | = | 13000.0 | nM | 4.89 |
| CHEMBL281542 | — | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL282618 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL28680 | — | IC50 | = | 22000.0 | nM | 4.66 |
| CHEMBL282803 | — | IC50 | = | 47000.0 | nM | 4.33 |