Assay Detail
Binding
CHEMBL804935
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Transcriptional activation in CV-1 cells expressing retinoid A receptor RAR gamma
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Cell Type | CV-1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Expert |
Publication
Conformationally defined retinoic acid analogues. 4. Potential new agents for acute promyelocytic and juvenile myelomonocytic leukemias.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.57 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL46398 | — | — | 1 | 8.70 |
| CHEMBL46397 | — | — | 1 | 6.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL46398 | — | EC50 | = | 2.0 | nM | 8.70 |
| CHEMBL46397 | — | EC50 | = | 370.0 | nM | 6.43 |