Assay Detail
Functional
CHEMBL805161
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In vitro inhibitory concentration required against human gastric adenocarcinoma SGC-7901 cell line
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SGC-7901 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and anticancer effect of chrysin derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 13 | 5.38 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL353283 | — | — | 1 | 5.66 |
| CHEMBL169645 | — | — | 1 | 5.60 |
| CHEMBL353368 | — | — | 1 | 5.55 |
| CHEMBL352508 | — | — | 1 | 5.54 |
| CHEMBL353729 | — | — | 1 | 5.44 |
| CHEMBL275391 | CHRYSIN DIMETHYL ETHER | — | 1 | 5.43 |
| CHEMBL171821 | — | — | 1 | 5.38 |
| CHEMBL367505 | CHRYSIN DIACETATE | — | 1 | 5.35 |
| CHEMBL55942 | — | — | 1 | 5.29 |
| CHEMBL117 | CHRYSIN | — | 1 | 5.24 |
| CHEMBL171039 | — | — | 1 | 5.23 |
| CHEMBL368559 | — | — | 1 | 5.19 |
| CHEMBL262919 | — | — | 1 | 5.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL353283 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL169645 | — | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL353368 | — | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL352508 | — | IC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL353729 | — | IC50 | = | 3600.0 | nM | 5.44 |
| CHEMBL275391 | CHRYSIN DIMETHYL ETHER | IC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL171821 | — | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL367505 | CHRYSIN DIACETATE | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL55942 | — | IC50 | = | 5100.0 | nM | 5.29 |
| CHEMBL117 | CHRYSIN | IC50 | = | 5800.0 | nM | 5.24 |
| CHEMBL171039 | — | IC50 | = | 5900.0 | nM | 5.23 |
| CHEMBL368559 | — | IC50 | = | 6400.0 | nM | 5.19 |
| CHEMBL262919 | — | IC50 | = | 8600.0 | nM | 5.07 |