Assay Detail
Functional
CHEMBL805168
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Cytoprotection of SH-SY5Y cells against veratridine-induced cytotoxicity
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SH-SY5Y |
| Confidence | 1 — Organism |
| Curated By | Expert |
Publication
2-Alkyl-4-arylimidazoles: structurally novel sodium channel modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.21 | 6.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL331942 | — | — | 1 | 6.42 |
| CHEMBL120306 | — | — | 1 | 6.37 |
| CHEMBL118603 | — | — | 1 | 6.35 |
| CHEMBL119139 | — | — | 1 | 6.12 |
| CHEMBL117331 | — | — | 1 | 6.11 |
| CHEMBL332257 | — | — | 1 | 6.09 |
| CHEMBL331513 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL331942 | — | IC50 | = | 380.0 | nM | 6.42 |
| CHEMBL120306 | — | IC50 | = | 430.0 | nM | 6.37 |
| CHEMBL118603 | — | IC50 | = | 450.0 | nM | 6.35 |
| CHEMBL119139 | — | IC50 | = | 760.0 | nM | 6.12 |
| CHEMBL117331 | — | IC50 | = | 770.0 | nM | 6.11 |
| CHEMBL332257 | — | IC50 | = | 810.0 | nM | 6.09 |
| CHEMBL331513 | — | IC50 | = | 1000.0 | nM | 6.00 |