Assay Detail
Functional
CHEMBL806480
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Cell-growth inhibition against SCC25 cell line
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SCC-25 |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Methotrexate analogues. 33. N delta-acyl-N alpha-(4-amino-4-deoxypteroyl)-L-ornithine derivatives: synthesis and in vitro antitumor activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.71 | 9.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18155 | — | — | 1 | 9.02 |
| CHEMBL422225 | — | — | 1 | 6.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18155 | — | IC50 | = | 0.96 | nM | 9.02 |
| CHEMBL422225 | — | IC50 | = | 400.0 | nM | 6.40 |