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Assay Detail

CHEMBL806796

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Compound along with 10 uM of erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA) was tested against mouse lymphoma T-cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Improved synthesis of 2'-deoxyformycin A and studies of its in vitro activity against mouse lymphoma of T-cell origin.
Rosowsky A, Solan VC, Gudas LJ.
J Med Chem (1985) 28 : 1096 -1099
PubMed 3874961 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 3 6.17 7.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL449329 DEOXYADENOSINE 1 7.52
CHEMBL471524 FORMYCIN 1 5.64
CHEMBL2311096 1 5.35

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL449329 DEOXYADENOSINE IC50 = 30.0 nM 7.52
CHEMBL471524 FORMYCIN IC50 = 2300.0 nM 5.64
CHEMBL2311096 IC50 = 4500.0 nM 5.35