Assay Detail
Binding
CHEMBL807100
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In vitro binding affinity was evaluated against mouse Somatostatin receptor type 2 (mSSTR-2)
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Potent, orally bioavailable somatostatin agonists: good absorption achieved by urea backbone cyclization.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 8.23 | 8.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL147319 | — | — | 1 | 8.70 |
| CHEMBL146022 | — | — | 1 | 8.00 |
| CHEMBL146128 | — | — | 1 | 8.00 |
| CHEMBL144146 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL147319 | — | Ki | = | 2.0 | nM | 8.70 |
| CHEMBL146022 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL146128 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL144146 | — | Ki | > | 10.0 | nM | - |