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Target Snapshot

CHEMBL3207 Target Snapshot

Somatostatin receptor type 2 · SINGLE PROTEIN · Mus musculus

13Compounds
4Assays
0Approved Drugs
17.0Activities
Free Research Context

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Broader Open DB context

Frame the target before identity details

Structured disease, protein, and project context should read before the lower-level identity rail.

As of 2026-09-14

Protein identity stays anchored to UniProt P30875. Use UniProt P30875 as the stable identity anchor, then attach disease evidence before program review.

Review focus
Protein anchor ready

Use UniProt P30875 as the stable identity anchor, then attach disease evidence before program review.

ChEMBL component mapping + Open Targets-ready proxy + ChEMBL 36 via Core Engine 2026-09-14
Open source guide
Identity Layer

Cross-source identity

Keep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.

This review treats Somatostatin receptor type 2 as ChEMBL target CHEMBL3207, mapped to UniProt P30875. Disease framing currently uses the Open Targets-ready proxy contract.

Review anchor
Somatostatin receptor type 2
SINGLE PROTEIN · Mus musculus
As of 2026-09-14
ChEMBL target ID
CHEMBL3207
Primary anchor for compounds, assays, approvals, and exports
ChEMBL 36 via Core Engine As of 2026-09-14
www.ebi.ac.uk
UniProt accession
P30875
Somatostatin receptor type 2
UniProt accession via ChEMBL component mapping As of 2026-09-14
www.uniprot.org
Disease evidence contract
Open Targets-ready proxy
ChEMBL drug mechanism + indication proxy
ChEMBL drug mechanism + indication proxy As of 2026-09-14
www.ebi.ac.uk

Reuse the same identifiers in notes, watch rules, exports, and review packs so provenance stays stable across surfaces.

Source Guidance

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UniProt Target Context
UniProt accession via ChEMBL component mapping

Start here when your first question is whether Somatostatin receptor type 2 is the right protein anchor across sources, using UniProt P30875 as the stable mapping.

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Disease Relevance & Evidence Level
ChEMBL drug mechanism + indication proxy

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Evidence Card
Review-ready rationale with source-aware context

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Overview

Basic Information

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UniProt Context

UniProt Target Context

Reviewable protein naming and mapping context for this target snapshot.

Protein LabelSomatostatin receptor type 2
UniProt AccessionP30875
Component TypeProtein
Sequence Length369 aa

Somatostatin receptor type 2

Source · UniProt accession via ChEMBL component mapping
Review Cue

How to read this target

Review this target as Somatostatin receptor type 2, mapped to UniProt P30875. Sequence length is 369 aa.

Mapped IDP30875
Review nameSomatostatin receptor type 2
OrganismMus musculus
Clinical Profile

Clinical Phase Distribution

1
Phase III
Assay Mix

Activity Type Distribution

IC5013.0
KI4.0
Lead Set

Top Inhibitors (by pChEMBL)

ChEMBL IDpChEMBLTypeValue (nM)Phase
CHEMBL1823872 9.55 IC50 0.28 Clinical
CHEMBL3350037 9.55 IC50 0.28 Preclinical
CHEMBL415860 9.55 IC50 0.28 Preclinical
CHEMBL147319 8.7 Ki 2.0 Preclinical
CHEMBL146022 8.0 Ki 10.0 Preclinical
CHEMBL146128 8.0 Ki 10.0 Preclinical
CHEMBL266469 7.88 IC50 13.13 Preclinical
CHEMBL421493 7.87 IC50 13.62 Preclinical
CHEMBL436783 7.81 IC50 15.6 Preclinical
Distribution

pChEMBL Value Distribution

0
5.0
0
5.5
0
6.0
0
6.5
0
7.0
6
7.5
2
8.0
1
8.5
0
9.0
3
9.5
pChEMBL
Assay Landscape

Assay Landscape

7
Total Assays
9
Tested Compounds
1
Assay Types
Binding — 7 assays, 9 compounds
BAO Format Assays Compounds Avg pChEMBL
single protein format 4 9 8.4
cell-based format 3 0

Confidence Score Distribution

Source · ChEMBL 36 via Core Engine